Colts' Donald Brown, Bob Sanders (Surprise!) Hurt in St. Louis
On the other side of the ball, defensive back Bob Sanders, who continues to make his case for "Most Fragile Player in the NFL", walked to the locker room with a trainer early in the fourth quarter.
Even with all the injury issues, Indianapolis smoked St. Louis, 42-6, to move to 6-0 on the year.
Brown had two carries for 58 yards, but left after his second run -- a 13-yarder -- with a strained left shoulder after taking a hard hit on his arm. He immediately went to the sideline and appeared to be in a substantial amount of pain.
Both Brown and Wayne were initially listed as questionable to return, but Wayne rejoined the Colts' offense after halftime. Brown stayed in the locker room for extra treatment. Joseph Addai led the Colts with 62 carries on the season, heading into Sunday, but Brown had 44. The only other running back to rush the ball was Chad Simpson, who had just three attempts.
Sanders, meanwhile, was making his 2009 debut after a knee injury sidelined him for Indianapolis' first six games. Sanders only played six games in 2008, four games in 2006, and has been simply unable to stay on the field.