But there were several other off-script gems this year that you may not have seen. Here are my top 10.
1) Senator, Secretary, What's the Diff?
First Lady Michelle Obama forgets what job Hillary Rodham Clinton has but makes up for it with a hilarious comeback.
2) Hair Today, Gone Tomorrow
California Republican Senate candidate Carly Fiorina gives viewers an indication of why she isn't Senator-Elect Fiorina in this clip, where she thinks her mic is turned off.
3) Street Thug
Rep. Bob Etheridge, D-N.C., was walking down a Washington street when he was approached by a young man asking him about the "Obama agenda," while someone else is holding a camera. Watch Etheridge go ballistic on them.
4) The Impersonator
Democratic New York Assemblyman Bob Reilly gives a speech where he mimics the voice of a man he met, Kyle, who he believes has cerebral palsy.
5) Hand Jive
During an interview at the Tea Party Convention, Sarah Palin looks down at her hand, as if referring to something that seems to be written on it.
6) Your Mother's Dead, or Not
Gaffe-prone Biden offers his condolensces to the Irish prime minister, only to realize that his mother is, in fact, still living.
7) Thanks for the Unemployed
Sen. Harry Reid, D-Nev., shows off his compassion for the unemployed, or something.
8) Stark Raving Mad
Republican candidate Phil Davidson really, really, really wants to be Stark County, Ohio, treasurer. Incredibly, he didn't win.
9) Broken Seal
During President Barack Obama's speech at Fortune Magazine's Most Powerful Women Summit, the Presidential Seal displayed in front of the podium falls, to the president's surprise and, in the end, the audience's delight.
10) Two-fer: Out of Their Cotton-Pickin' Minds
And, finanlly, this year also featured two reporters with a knack for choosing just the wrong adjective when it comes to the country's first African-American president.
Here's former CNN host Rick Sanchez calling President Obama the cotton-picking president and then apologizing after viewers responded negatively.
And here's Newsweek editor Julia Reed using the same phrase.
A.G. Vargas is a freelance writer living in New York City.
Related: Best Gaffes, International Edition.