Uncle Joe is actor Joe Estevez, who, in the family tradition, has had a long acting career that includes films such as "Beach Babes From Beyond," "San Franpsycho" and the upcoming drama "Doonby."
Although Estevez hasn't had the public acclaim of his nephew or his brother, Martin Sheen, or even his other nephew, Emilio Estevez, he loves Charlie and wants what's best for him.
Although Sheen has dismissed his dad's comments that addiction is like cancer as "bollocks," perhaps he's more open to having a heart-to-heart with Uncle Joe.
"I want to tread lightly here," Estevez told AOL News in an exclusive interview. "Charlie is on his own journey. I respect it and love him unconditionally, and I am here if he wants to talk.
"My heart breaks for him. I know he's going through a lot of pain."
Because Estevez has known Sheen from birth, he sees the situation differently than the average person might.
For instance, an average TV viewer might hear such quotes as, "I got magic and I've got poetry in my fingertips, you know, most of the time, and this includes naps. I'm an F-18, bro," and believe Sheen must be on drugs.
"When I heard the interviews, I was reminded of [Beat writer] Jack Kerouac, that stream-of-consciousness," Estevez said. "You know, he's given millions of dollars to charity and never says a word about it.
"He is not a selfish man, but he's on a journey, and we wish we could help him along with it."
Estevez knows what's that like.
A few years ago, he decided that he wasn't satisfied with his own career.
"I had a talk with myself and a lot of praying and meditating about making movies that make a difference," he said. "I asked God, 'Can you send me movies that do this that I can also make money at?' And God does listen."
Case in point is his upcoming film "Doonby," which debuts in July. It features former "Dukes of Hazzard" star John Schneider as a mysterious stranger who comes into a small town and falls in love with the spoiled daughter of Estevez's character, the local doctor.
"I'm the bad guy, but it's true that the villainous roles are often the best because you get more leeway with the character," Estevez said.
Perhaps his nephew can relate.